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Publikationen

2025

1. Double heterozygous pathogenic variants in BRCA2 and CHEK2 in a girl with adrenocortical carcinoma

2. Hereditäres Mammakarzinom

3. Investigation of Modal Characteristics of Silicon Nitride Ridge Waveguides for Enhanced Refractive Index Sensing

2024

1. Individualized targeted treatment in a case of a rare TFG::ROS1 fusion positive inflammatory myofibroblastic tumor (IMT)

2. Double Heterozygous Pathogenic Variants in TP53 and CHEK2 in Boy with Undifferentiated Embryonal Sarcoma of the Liver

3. Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer

2023

1. Th2/Th17 cell associated cytokines found in seroma fluids after breast cancer surgery

2. Beyond germline genetic testing – heterozygous pathogenic variants in PMS2 in two children with Osteosarcoma and Ependymoma

3. Genomic Complexity as a Biomarker to De-Escalate Adjuvant Imatinib Treatment in High-Risk Gastrointestinal Stromal Tumor

2022

1. Evolutionary patterns of chromosomal instability and mismatch repair deficiency in proximal and distal colorectal cancer

2. Structural Organization of Human Full-Length PAR3 and the aPKC-PAR6 Complex

2021

1. Expression of the Neural REST/NRSF-SIN3 Transcriptional Corepressor Complex as a Target for Small-Molecule Inhibitors

2019

1. An initial evaluation of cytotoxicity, genotoxicity and antibacterial effectiveness of a disinfection liquid containing silver nanoparticles alone and combined with a glass-ionomer cement and dentin bonding systems

2. Looking for the hidden mutation: Bannayan-Riley-Ruvalcaba syndrome caused by constitutional and mosaic 10q23 microdeletions involving PTEN and BMPR1A

3. The FlpTRAP system for purification of specific, endogenous chromatin regions

4. The ATPase BRG1/SMARCA4 is a protein interaction platform that recruits BAF subunits and the transcriptional repressor REST/NRSF in neural progenitor cells

2018

1. Hemoglobin polymerization via disulfide bond formation in the hypoxia-tolerant turtle Trachemys scripta: implications for antioxidant defense and O₂ transport

2. Folding and assembly defects of pyruvate dehydrogenase deficiency-related variants in the E1α subunit of the pyruvate dehydrogenase complex

3. Human cellular models of medium spiny neuron development and Huntington disease

4. Modulating the Expression Strength of the Baculovirus/Insect Cell Expression System: A Toolbox Applied to the Human Tumor Suppressor SMARCB1/SNF5

5. Vectors for Expression of Signal Peptide-Dependent Proteins in Baculovirus/Insect Cell Systems and Their Application to Expression and Purification of the High-Affinity Immunoglobulin Gamma Fc Receptor I in Complex with Its Gamma Chain

6. Models of the complement C1 complex

2017

1. Synergistic anti-cancer effects of epigenetic drugs on medulloblastoma cells

2. Reply to Arlaud et al.: Structure of the C1 complex and the unbound C1r2s2 tetramer

3. Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

4. Expression of Flp Protein in a Baculovirus/Insect Cell System for Biotechnological Applications

5. Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target

2016

1. Aspergillus galactomannan detection in comparison to a real-time PCR assay in serum samples from a high-risk group of patients

2. Use of human stem cells in Huntington disease modeling and translational research

3. A forensic hypothesis for the mystery of al-Hasan's death in the 7th century: Mercury(I) chloride intoxication

4. Virulence of Bacteria Colonizing Vascular Bundles in Ischemic Lower Limbs

2015

1. Dual tagging as an approach to isolate endogenous chromatin remodeling complexes from Saccharomyces cerevisiae

2. In Vitro Differentiation of Human Neural Progenitor Cells Into Striatal GABAergic Neurons

3. Structural insights into the initiating complex of the lectin pathway of complement activation

2014

1. Staphylococcus aureus nasal carriage in Ukraine: antibacterial resistance and virulence factor encoding genes

2. Invasive candidiasis serological diagnosis in solid organ transplant recipients

3. Strep-tag II and Twin-Strep based cassettes for protein tagging by homologous recombination and characterization of endogenous macromolecular assemblies in Saccharomyces cerevisiae

4. Candida nivariensis in comparison to different phenotypes of Candida glabrata

5. Trends in antifungal susceptibility of Candida species--one year observation

6. Polymerase chain reaction melting profiles of Candida glabrata clinical isolates in solid organ transplant recipients in comparison to the other group of surgical patients

2013

1. HistoViewer: an interactive e-learning platform facilitating group and peer group learning

2. Drug loading of polymeric micelles

2011

1. Three-dimensional reconstruction of Trypanosoma brucei editosomes using single-particle electron microscopy

2. Single molecule microscopy methods for the study of DNA origami structures

3. Visualization of bionanostructures using transmission electron microscopical techniques

4. Acinetobacter baumannii multidrug-resistant strain occurrence in liver recipients with reference to other high-risk groups

5. The probability of the Acinetobacter baumannii strain clonal spreading in donor-recipient systems, as confirmed by the molecular analysis of randomly amplified polymorphic DNA

2010

1. Characterization of tailor-made copolymers of oligo(ethylene glycol) methyl ether methacrylate and N,N-dimethylaminoethyl methacrylate as nonviral gene transfer agents: influence of macromolecular structure on gene vector particle properties and transf

2. Malignant transformation of an untreated congenital sacrococcygeal teratoma: a amplification at 8q and 12p detected by comparative genomic hybridization

3. 3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core

4. Merging molecular electron microscopy and mass spectrometry by carbon film-assisted endoproteinase digestion

5. Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis

6. An approach for de novo structure determination of dynamic molecular assemblies by electron cryomicroscopy

2009

1. Self-assembly of ternary insulin-polyethylenimine (PEI)-DNA nanoparticles for enhanced gene delivery and expression in alveolar epithelial cells

2. Snapshots of the RNA editing machine in trypanosomes captured at different assembly stages in vivo

3. Self-assembly of a nanoscale DNA box with a controllable lid

2008

1. An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

2. GraFix: sample preparation for single-particle electron cryomicroscopy

3. Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy

2007

1. Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes

2006

1. Comparative genomic hybridization analysis on male breast cancer

2. Differential diagnosis of gastrointestinal leiomyoma versus gastrointestinal stromal tumor

3. Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy

4. Crystal structure of a core spliceosomal protein interface

2005

1. Human papilloma virus infection in a recurrent squamous cell carcinoma associated with severe Crohn's disease

2. Advantages of CCD detectors for de novo three-dimensional structure determination in single-particle electron microscopy

3. Major conformational change in the complex SF3b upon integration into the spliceosomal U11/U12 di-snRNP as revealed by electron cryomicroscopy

4. Aerosolized nanogram quantities of plasmid DNA mediate highly efficient gene delivery to mouse airway epithelium

2003

1. Automatic CTF correction for single particles based upon multivariate statistical analysis of individual power spectra

2. Corrim-based alignment for improved speed in single-particle image processing

3. Molecular architecture of the multiprotein splicing factor SF3b