Integration gezielter Radionuklid-Therapie in die Konditionierung
Optimierte medikamentöse und zelluläre Therapie des AML Rezidivs nach alloSZT
Optimierte Ernährung unter alloSZT
Registerstudien: u.a.
allogene Zweit-Transplantation bei AML und MDS
Einsatz prophylaktischer Transfusion von Spenderlymphozyten
GvHD Prophylaxe mit reduziertem ptCy
Experimentelle Studien:
Spatial Transcriptomics zur Detektion von Immune Escape Mechanismen bei leukämischen Erkrankungen mit Rezidiv
Immune Escape bei extramedullären leukämischen Erkrankungen
Einfluss von Checkpoint Inhibitoren auf die allogene Immunreaktion
Velázquez GF, Weller JF, Rubeck A, Arndt T, Schiele S, Mezger M, Lengerke C, Bethge W, Trepel M, Müller G, Christopeit M, Schmid C. Prophylactic and pre-emptive donor lymphocyte infusion in patients with acute myeloid leukaemia and myelodysplastic syndrome - Validation of current recommendations and proposal of a modified outcome assessment Haematologica. 2025 Apr 24. doi: 10.3324/haematol.2024.287206
Giuliano Filippini Velázquez,Philipp Anand, Joudi Abdulmajid, Xiaojia Feng, Jan Frederic Weller, Klaus Hirschbuehl, Helga Schmetzer; Christoph Schmid* Clinical Stabilization of a Highly Refractory Acute Myeloid Leukaemia Under Individualized Treatment with Immune Response Modifying Drugs by In Vivo Generation of Dendritic Cells of Leukaemic Origin (DCleu) and Modulation of Effector Cells and Immune Escape Mechanisms Biomarker Research 2025 Aug 15;13(1):104.doi: 10.1186/s40364-025-00817-8
Schmälter AK, Labopin M, Versluis J, Gallego Hernanz MP, Eder M, von dem Borne P, Socié G, Chevallier P, Forcade E, Neubauer A, Baron F, Bazarbachi A, Bug G, Nagler A, Schmid C*, Esteve J, Mohty M, Ciceri F.The role of allogeneic stem cell transplantation in acute myeloid leukemia with translocation t(8;16)(p11;p13)Am J Hematol. 2025 Jan;100(1):85-92. doi: 10.1002/ajh.27496.
Ann-Kristin Schmaelter, Maud Ngoya, Jacques-Emmanuel Galimard, Ali Bazarbachi, Jürgen Finke, Nicolaus Kröger, Martin Bornhauser, Matthias Stelljes, Friedrich Stölzel, Johanna Tischer, Thomas Schroeder, Peter Dreger, Igor-Wolfgang Blau, Bipin Savani, Sebastian Giebel, Jordi Esteve, Nagler Arnon, Christoph Schmid* Fabio Ciceri, and Mohamad Mohty Continuously improving outcome over time after second allogeneic stem cell transplantation in relapsed acute myeloid leukemia - an EBMT registry analysis of 1540 patients. Blood Cancer J. 2024 May 2;14(1):76.doi: 10.1038/s41408-024-01060-4
Simona Pagliuca MD, Christoph Schmid MD (contr. equally), , Nicole Santoro MD, Federico Simonetta MD, Giorgiia Battipaglia MD, Prof. Thierry Guillaume MD, Raffaella Greco MD, Prof. Francesco Onida MD, Isabel Sánchez-Ortega MD, Prof. Ibrahim Yakoub Agha MD, Prof. Jurgen Kuball MD, Prof. Mette D. Hazenberg MD, Annalisa Ruggeri MD Donor lymphocyte infusion after allogeneic haematopoietic cell transplantation for haematological malignancies: basic considerations and best practice recommendations from the Practice Harmonization and Guidelines Committee and the Cellular Therapy and Immunobiology Working Party of the EBMT. Lancet Haematol. 2024 Jun;11(6):e448-e458. doi: 10.1016/S2352-3026(24)00098-X PMID: 38796194
