Publikationen
Prof. Dr. Martin Trepel
- Wei C, Jiang W, Wang R, Zhong H, He H, Gao X, Zhong S, Yu F, Guo Q, Zhang L, Schiffelers LDJ, Zhou B, Trepel M, Schmidt FI, Luo M, Shao F: Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 2024 in press
- Schlosser P, Schiwitza A, Klaus J, Hieke-Schulz S, Szic KSV, Duyster J, Trepel M, Zirlik K, Schumacher M, Claus R: Conditional survival to assess prognosis in patients with chronic lymphocytic leukemia. Ann Hematol. in press
-
Liebich A, Enke JS, Reitsam NG, Trepel M, Wienand G, Bundschuh RA, Pfob CH, Dierks A, Lapa C, Kircher M: SSTR Antagonists as Theranostic Option in Small Cell Lung Cancer. Am J Respir Crit Care Med., in press
-
Höhne K, Wagenknecht A, Maier C, Engelhard P, Goldmann T, Schließmann SJ, Plönes T, Trepel M, Eibel H, Müller-Quernheim J, Zissel G: Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6. Cells 13, 238, 2024
- Enke JS, Reitsam NG, Grosser B, Kircher M, Dierks A, Bundschuh RA, Wienand G, Uhrmacher L, Trepel M, Schottelius M, Lapa C, Pfob CH: C-X-C Motif Chemokine Receptor 4-Directed Scintigraphy of Multiple Myeloma Using [99mTc]Tc-PentixaTec. J Nucl Med. 65, 163-164, 2024
- Grosser B, Emmerson J, Reitsam NG, Cunningham D, Nankivell M, Langley RE, Allum WH, Trepel M, Märkl B, Grabsch HI: Stroma AReactive Invasion Front Areas (SARIFA) improves prognostic risk stratification of perioperative chemotherapy treated oesophagogastric cancer patients from the MAGIC and the ST03 trial. Br J Cancer 130, 457-466, 2023
- Enke JS, Gäble A, Reitsam NG, Schaller T, Trepel M, Hirschbühl K, Welzel J, Dierks A, Kircher M, Lapa C: Granulomatous dermatitis: a rare pitfall in lymphoma staging with [18F]FDG-PET/CT. Eur J Nucl Med Mol Imaging 50, 3479-3480, 2023
- Dierks A Gäble A, Rinscheid A, Wienand G, Pfob CH, Kircher M, Enke JS, Janzen T, Patt M, Trepel M, Weckermann D, Bundschuh RA, Lapa C: First Safety and Efficacy Data with the Radiohybrid 177Lu-rhPSMA-10.1 for the Treatment of Metastatic Prostate Cancer. J Nucl Med. 123, 266741, 2023
- Rinscheid A, Gäble A, Wienand G, Pfob C, Dierks A, Kircher M, Trepel M, Weckermann D, Lapa C, Bundschuh RA.: An Intrapatient Dosimetry Comparison of 177Lu-rhPSMA-10.1 and 177Lu-PSMA-I&T in Patients with Metastatic Castration-Resistant Prostate Cancer. J Nucl Med. 64, 1918-1924, 2023
- Illert AL, Stenzinger A, Bitzer M, Horak P, Gaidzik VI, Möller Y, Beha J, Öner Ö, Schmitt F, Laßmann S, Ossowski S, Schaaf CP, Hallek M, Brümmendorf TH, Albers P, Fehm T, Brossart P, Glimm H, Schadendorf D, Bleckmann A, Brandts CH, Esposito I, Mack E, Peters C, Bokemeyer C, Fröhling S, Kindler T, Algül H, Heinemann V, Döhner H, Bargou R, Ellenrieder V, Hillemanns P, Lordick F, Hochhaus A, Beckmann MW, Pukrop T, Trepel M, Sundmacher L, Wesselmann S, Nettekoven G, Kohlhuber F, Heinze O, Budczies J, Werner M, Nikolaou K, Beer AJ, Tabatabai G, Weichert W, Keilholz U, Boerries M, Kohlbacher O, Duyster J, Thimme R, Seufferlein T, Schirmacher P, Malek NP: The German Network for Personalized Medicine to enhance patient care and translational research. Nature Medicine 29, 1298-1301, 2023
- Claaß LV, Mayr P, Paschold L, Weber T, Terziev D, Jehs B, Brill R, Dober J, Märkl B, Wickenhauser C, Czapiewski P, Trepel M, Claus R, Binder M: No association of malignant B-cell non-Hodgkin lymphomas with ipsilateral SARS-CoV-2 vaccination. Cancer Med. 12, 9313-9321, 2023
- Filippini Velázquez G, Schiele S, Gerken M, Neumaier S, Hackl C, Mayr P, Klinkhammer-Schalke M, Illerhaus G, Schlitt HJ, Anthuber M, Kröncke T, Messmann H, Märkl B, Schmid C, Trepel M, Müller G, Claus R, Hackanson B: Predictive preoperative clinical score for patients with liver-only oligometastatic colorectal cancer. ESMO Open 7, 100470, 2022
- Remes A, Körbelin J, Arnold C, Rowedder C, Heckmann M, Mairbäurl H, Frank D, Korff T, Frey N, Trepel M, Müller OJ: Adeno-Associated Virus-Mediated Gene Transfer of Inducible Nitric Oxide Synthase to an Animal Model of Pulmonary Hypertension. Hum Gene Ther 33, 959-967, 2022
- Lüke F, Haller F, Utpatel K, Krebs M, Meidenbauer N, Scheiter A, Spoerl S, Heudobler D, Sparrer D, Kaiser U, Keil F, Schubart C, Tögel L, Einhell S, Dietmaier W, Huss R, Dintner S, Sommer S, Jordan F, Goebeler ME, Metz M, Haake D, Scheytt M, Gerhard-Hartmann E, Maurus K, Brändlein S, Rosenwald A, Hartmann A, Märkl B, Einsele H, Mackensen A, Herr W, Kunzmann V, Bargou R, Beckmann MW, Pukrop T, Trepel M, Evert M, Claus R, Kerscher A: Identification of Disparities in Personalized Cancer Care-A Joint Approach of the German WERA Consortium. Cancers 14, 5040, 2022
- Jordan F, Trepel M, Claus R: Restoring Immune Mediated Disease C76. Jordan F, Trepel M, Claus R: Restoring Immune Mediated Disease Control by Ipilimumab Re-exposition in a Heavily pretreated Patient With MSI-H mCRC. Clin Colorectal Cancer 21, e148-e151, 2022
- Mayr P, Grünewald T, Filippini Velazquez G, Rank A, Schmid C, Harloff M, Märkl B, Trepel M, Hirschbühl K, Pfeiffer T, Claus R: Transfusion-refractory pancytopenia with MDS-like morphologic alterations of the bone marrow in a 29-year old man: A mimicry manifestation caused by scurvy. Br J Haematol 197, 627-630, 2022
- Olschewski P, Kaspar-Ott I, Koller S, Schenkirsch G, Trepel M, Hertig E: Associations between Weather, Air Quality and Moderate Extreme Cancer-Related Mortality Events in Augsburg, Southern Germany. Int J Environ Res Public Health 8, 11737, 2021
- Staquicini FI, Hajitou A, Driessen WH, Proneth B, Cardó-Vila M, Staquicini DI, Markosian C, Hoh M, Cortez M, Hooda-Nehra A, Jaloudi M, Silva IT, Buttura J, Nunes DN, Dias-Neto E, Eckhardt B, Ruiz-Ramírez J, Dogra P, Wang Z, Cristini V, Trepel M, Anderson R, Sidman RL, Gelovani JG, Cristofanilli M, Hortobagyi GN, Bhujwalla ZM, Burley SK, Arap W, Pasqualini R: Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer. Elife 10, e65145, 2021
- Jordan F, Huber S, Sommer S, Schenkirsch G, Frühwald MC, Trepel M, Claus R, Kuhlen M: A Retrospective 5-Year Single Center Study Highlighting the Risk of Cancer Predisposition in Adolescents and Young Adults. Cancers 13, 3033 2021
- Alvarez-Vergara MI, Rosales-Nieves AE, March-Diaz R, Rodriguez-Perinan G, Lara-Ureña N, Ortega-de San Luis C, Sanchez-Garcia MA, Martin-Bornez M, Gómez-Gálvez P, Vicente-Munuera P, Fernandez-Gomez B, Marchena MA, Bullones-Bolanos AS, Davila JC, Gonzalez-Martinez R, Trillo-Contreras JL, Sanchez-Hidalgo AC, del Toro R, Scholl FG, Herrera E, Trepel M, Körbelin J, Escudero LM, Villadiego J, Echevarria M, de Castro F, Gutierrez A, Rabano A, Vitorica J, Pascual A: Non-productive angiogenesis disassembles Aß plaque-associated blood vessels. Nature Communications 12, 3098, 202
- Waidhauser J, Martin B, Trepel M, Märkl B: Can low autopsy rates be increased? Yes, we can! Should postmortem examinations in oncology be performed? Yes, we should! A postmortem analysis of oncological cases. Virchows Arch. 478, 310-308, 2021
- Waidhauser J, Schuh A, Trepel M, Schmälter AK, Rank A: Chemotherapy markedly reduces B cells but not T cells and NK cells in patients with cancer. Cancer Immunol. Immunother 69, 147-157, 2020
- Schaller T, Hirschbühl K, Burkhardt K, Braun G, Trepel M, Märkl B, Claus R: Postmortem Examination of Patients With COVID-19. JAMA 323, 2518-2520, 2020
- Grundmann N, Meisinger C, Trepel M, Müller-Nordhorn J, Schenkirsch G, Linseisen J: Trends in cancer incidence and survival in the Augsburg study region-results from the Augsburg cancer registry. BMJ Open 10, e036176, 2020
- Hirschbuehl K, Rank A, Pfeiffer T, Schaller T, Haeckel T, Roeling J, Vlasenko D, Trepel M, Schmid C: Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report. J. Hematol. 8, 83-85, 2019Hirschbuehl K, Rank A, Pfeiffer T, Schaller T, Haeckel T, Roeling J, Vlasenko D, Trepel M, Schmid C: Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report. J. Hematol. 8, 83-85, 2019
- Schmutz M, Schaller T, Kubuschok B, Fleischmann C, Hirschbühl K, Dintner S, Häckel T, Märkl B, Trepel M, Claus R: [Periodic fever and pancytopenia in a 35-year-old patient] Periodisches Fieber und Panzytopenie bei einem 35‑jährigen Patienten. Internist 60, 1305-1310, 2019
- Waidhauser J, Bornemann A, Trepel M, Märkl B: Frequency, localization, and types of gastrointestinal stromal tumor-associated neoplasia. World J. Gastroenterol. 25, 4261-4277, 2019
- Gomes de Castro MA, Wildhagen H, Sograte-Idrissi S, Hitzing C, Binder M, Trepel M, Engels N, Opazo F: Differential organization of tonic and chronic B cell antigen receptors in the plasma membrane. Nature Commun. 10, 820, 2019
- Eichhoff AM, Börner K, Albrecht B, Schäfer W, Baum N, Haag F, Körbelin J, Trepel M, Braren I, Grimm D, Adriouch S, Koch-Nolte F: Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors. Mol Ther Methods Clin Dev. 15, 211-220, 2019
- Jordan F, Grundmann N, Schenkirsch G, Märkl B, Messmann H, Anthuber M, Schmid C, Trepel M: Impact of Primary tumor localization on the efficacy of bevacizumab in metastatic colorectal cancer. Anticancer Res. 38, 5539-5546, 2018
- Körbelin J, Hunger A, Alawi M, Sieber T, Binder M, Trepel M: Optimization of design and production strategies for novel adeno-associated viral display peptide libraries. Gene Ther. 24, 470-481, 2017
- Dogbevia GK, Töllner K, Körbelin J, Bröer S, Ridder DA, Grasshoff H, Brandt C, Wenzel J, Straub BK, Trepel M, Löscher W, Schwaninger M: Gene Therapy Decreases Seizures in a Model of Incontinentia Pigmenti. Ann Neurol. 82, 93-104, 2017
- Braig F, Kriegs M, Voigtlaender M, Habel B, Grob T, Biskup K, Blanchard V, Sack M, Thalhammer A, Ben Batalla I, Braren I, Laban S, Danielczyk A, Goletz S, Jakubowicz E, Märkl B, Trepel M, Knecht R, Riecken K, Fehse B, Loges S, Bokemeyer C, Binder M: Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism. Cancer Res. 77, 1188-1199, 2017
- Körbelin J, Trepel M: How to Successfully Screen Random Adeno-Associated Virus Display Peptide Libraries In Vivo. Hum. Gene Ther. Methods 3, 109-123, 2017
- 56. Fichtner M, Spies E, Seismann H, Riecken K, Engels N, Gösch B, Dierlamm J, Gerull H, Nollau P, Klapper W, Dreyling M, Binder M, Trepel M: Complementarity determining region-independent recognition of a superantigen by B-cell antigen receptors of mantle cell lymphoma. Haematologica 101, e378-381, 2016
- Körbelin J, Sieber T, Michelfelder S, Lunding L, Spies E, Hunger A, Alawi M, Rapti K, Indenbirken D, Müller OJ, Pasqualini R, Arap W, Kleinschmidt JA, Trepel M: Pulmonary targeting of adeno-associated viral vectors by NEXT-generation sequencing-guided screening of random capsid displayed peptide libraries. Mol. Ther. 24, 1050-1061, 2016
- Körbelin J, Dogbevia G, Michelfelder S, Ridder DA, Hunger A, Wenzel J, Seismann H, Lampe M, Bannach J, Pasparakis M, Kleinschmidt JA, Schwaninger M*, Trepel M: A brain microvasculature endothelial cell-specific viral vector for the treatment of neurovascular and neurological diseases. EMBO Mol. Med. 8, 609-625, 2016
- Pilger A, Tsilimparis N, Bockhorn M, Trepel M, Dreimann M: Combined modified en bloc corpectomy with replacement of the aorta in curative interdisciplinary treatment of a large osteosarcoma infiltrating the aorta. Eur. Spine J. 25 Suppl 1, 58-62, 2016
- Spies E, Fichtner M, Müller F, Krasemann S, Illerhaus G, Glatzel M, Binder M, Trepel M: Comment on "Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins". J. Immunol. 195, 4549-4550, 2015
- Bannas P, Lenz A, Kunick V, Well L, Fumey W, Rissiek B, Haag F, Schmid J, Schütze K, Eichhoff A, Trepel M, Adam G, Ittrich H, Koch-Nolte F: Molecular imaging of tumors with nanobodies and antibodies: Timing and dosage are crucial factors for improved in vivo detection. Contrast Media Mol. Imaging 10, 367-378, 2015
- Trepel M, Körbelin J, Spies E, Heckmann MB, Hunger A, Fehse B, Katus HA, Kleinschmidt JA, Müller OJ, Michelfelder S: Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors. Gene Ther. 22, 840-847, 2015
- Voigtlaender M, Vogler B, Trepel M, Panse J, Jung R, Bokemeyer C, Bacher U, Binder M.: Hospital population screening reveals overrepresentation of CD5- monoclonal B-cell lymphocytosis and monoclonal gammopathy of undetermined significance of IgM type. Ann. Hematol. 94, 1559-1565, 2015
- Sieber T, Hare E, Hofmann H, Trepel M: Biomathematical description of synthetic peptide libraries. PLoS One 10, e0129200, 2015
- Bannas P, Lenz A, Kunick V, Fumey W, Rissiek B, Schmid J, Haag F, Leingärtner A, Trepel M, Adam G, Koch-Nolte F: Validation of nanobody and antibody based in vivo tumor xenograft NIRF-imaging experiments in mice using ex vivo flow cytometry and microscopy. J. Vis. Exp., 6, e52462, 2015
- Rissiek A, Schulze C, Bacher U, Schieferdecker A, Thiele B, Jacholkowski A, Flammiger A, Horn C, Haag F, Tiegs G, Zirlik K, Trepel M, Tolosa E, Binder M: Multidimensional scaling analysis identifies pathological and prognostically relevant profiles of circulating T-cells in chronic lymphocytic leukemia. Int. J. Cancer 135, 2370-2379, 2014
- Thiele B, Kloster M, Alawi M, Indenbirken D, Trepel M, Grundhoff A, Binder M: Next-generation sequencing of peripheral B-lineage cells pinpoints the circulating clonotypic cell pool in multiple myeloma. Blood 123, 3618-3621, 2014
- Tachezy M, Gebauer F, Petersen C, Arnold D, Trepel M, Wegscheider K, Schafhausen P, Bockhorn M, Izbicki JR, Yekebas E: Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191749). BMC Cancer 14, 411, 2014
- Bannas P, Well L, Lenz A, Rissiek B, Haag F, Schmid J, Hochgräfe K, Trepel M, Adam G, Ittrich H, Koch-Nolte F: In vivo near-infrared fluorescence targeting of T cells: comparison of nanobodies and conventional monoclonal antibodies. Contrast Media Mol Imaging 9, 135-142, 2014
- Flammiger, A, Weisbach L, Huland H, Tennstedt P, Simon R, Minner S, Bokemeyer C, Sauter G, Schlomm T, Trepel M: High tissue density of FOXP3+ T cells is associated with clinical outcome in prostate cancer. Eur J Cancer 49, 1273-1279, 2013
- Binder M, Müller F, Frick M, Wehr C, Simon F, Leistler B, Veelken H, Mertelsmann R, Trepel M: CLL B cell receptors can recognize themselves: alternative epitopes and structural clues for autostimulatory mechanisms in CLL. Blood 121, 239-241, 2013
- Flammiger A, Bayer F, Cirugeda-Kühnert A, Huland H, Tennstedt P, Simon R, Minner S, Bokemeyer C, Sauter G, Schlomm T, Trepel M: Intratumoral T- but not B-lymphocytes are related to clinical outcome in prostate cancer. APMIS 120, 901-908, 2012
- Varadi K, Michelfelder S, Korff T, Hecker M, Trepel M, Katus HA, Kleinschmidt JA, Müller OJ: Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors. Gene Ther. 19, 800-809, 2012
- Trepel M, Martens V, Doll C, Rahlff J, Gösch B, Loges S, Binder M: Phenotypic Detection of Clonotypic B Cells in Multiple Myeloma by Specific Immunoglobulin Ligands Reveals their Rarity in Multiple Myeloma. PLoS One 7, e31998, 2012.
- Naumer M, Ying Y, Michelfelder S, Reuter A, Trepel M, Müller OJ, Kleinschmidt JA: Development and validation of novel AAV2 random libraries displaying peptides of diverse lengths and at diverse capsid positions. Hum Gene Ther. 23, 492-507, 2012
- Wehr C, Müller F, Schüler J, Tomann T, Nitschke C, Seismann H, Spillner E, Klingner K, Schneider-Merck T, Binder M, Fiebig HH, Mertelsmann R, Trepel M: Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model. Int. J. Cancer 131, E10-20, 2012
- Müller-Schmah CI, Solari L, Weis R, Pfeifer D, Scheibenbogen C, Trepel M, May AM, Engelhardt R, M Lübbert M: Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia. Ann. Hematology 91, 27-32, 2012
- Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W: Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc. Natl. Acad. Sci. USA 108, 18637-18642, 2011
- Michelfelder S, Varadi K, Raupp C, Hunger A, Körbelin J Pahrmann C, Schrepfer S, Müller OJ, Kleinschmidt JA, Trepel M: Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo, PLoS One 6, e23101, 2011
- Binder M, Müller F, Jackst A, Léchenne B, Pantic M, Bacher U, Eulenburg CZ, Veelken H, Mertelsmann R, Pasqualini R, Arap W, Trepel M: B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia. Cancer 117, 1891-1900, 2011
- Binder M, Léchenne B, Ummanni R, Scharf C, Balabanov S, Trusch M, Schlüter H, Braren I, Spillner E, Trepel M: Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells. PLoS One 5, e15992, 2010
- Kohlschütter J, Michelfelder S, Trepel M: Novel Cytotoxic Vectors Based on Adeno-Associated Virus. Toxins 2, 2754-2768, 2010
- Ying Y, Müller OJ, Goehringer C, Leuchs B, Trepel M, Katus HA, Kleinschmidt JA: Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library. Gene Therapy 17, 980-990, 2010
- Trepel M, Stoneham CA, Eleftherohorinou H, Mazarakis ND, Pasqualini R, Arap W, Hajitou A: A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Mol. Cancer Ther. 8, 2383-2391, 2009
- Michelfelder S, Kohlschütter J, Skorupa A, Pfennings S, Müller O, Kleinschmidt JA, Trepel M: Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries. PLoS ONE 4, e5122, 2009
- Michelfelder S, Lee M-K, de Lima-Hahn E, Wilmes T, Kaul F, Müller O, Kleinschmidt JA, Trepel M: Vectors selected from adeno-associated viral display peptide libraries for leukemia cell-targeted cytotoxic gene therapy. Exp. Hematol. 35, 1766–1776, 2007
- Binder M, Vögtle FN, Michelfelder S, Müller F, Illerhaus G, Sundararajan S, Mertelsmann R, Trepel M: Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab. Cancer Res. 67, 3518-3523, 2007
- Hajitou A, Rangel R, Trepel M, Soghomonyan S, Gelovani JG, Alauddin MM, Pasqualini R, Arap W: Design and construction of targeted AAVP vectors for mammalian cell transduction. Nature Protocols 2, 523-531, 2007
- Soghomonyan S, Hajitou A, Rangel R, Trepel M, Pasqualini R, Arap W, Gelovani JG, Alauddin MM: Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU. Nature Protocols 2, 416-423, 2007
- Jäger S, Jahnke A, Wilmes T, Adebahr S, Vögtle FN, deLima-Hahn E, Pfeifer D, Berg T, Lübbert M, Trepel M: Leukemia targeting ligands isolated from phage display peptide libraries. Leukemia 21, 411-420, 2007
- Waterkamp DA, Müller OJ, Ying Y, Trepel M, Kleinschmidt JA: Isolation of targeted AAV2 vectors from novel virus display libraries. J. Gene Med. 8, 1307-1319, 2006
- Binder M, Otto F, Mertelsmann R, Veelken H, Trepel M: The epitope recognized by rituximab. Blood 108, 1975-1978, 2006
- Hajitou A, Trepel M, Lilley CE, Soghomonyan S, Alauddin M, Marini FC, Restel BH, Ozawa MG, Moya CA, Rangel R, Sun Y, Zaoui K, Schmidt M, von Kalle C, Weitzman MD, Gelovani JG, Pasqualini R, Arap W: A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell 125, 385-398, 2006
- Yao VJ, Ozawa MG, Trepel M, Arap W, McDonald DM, Pasqualini R: Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection. Am. J. Pathol. 166, 625-636, 2005
- Müller CI, Trepel M, Kunzmann R, Lais A, Engelhardt R, Lübbert M: Hematologic and molecular spontaneous remission following sepsis in acute monoblastic leukemia with translocation (9;11): a case report and review of the literature. Eur. J. Haematol. 73, 62–66, 2004
- Marchiò S, Lahdenranta J, Schlingemann RO, Valdembri D, Wesseling P, Arap MA, Hajitou A, Ozawa MG, Trepel M, Giordano RJ, Nanus DM, Dijkman HBPM, Oosterwijk E, Sidman RL, Cooper MD, Bussolino F, Pasqualini R, Arap W: Aminopeptidase A is a functional target in angiogenic blood vessels. Cancer Cell 5, 151-162, 2004
- Müller OJ*, Kaul F*, Weitzman MD, Pasqualini R, Arap W, Kleinschmidt JA*, Trepel M*: Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nature Biotechnology 21, 1040-1046, 2003
- Tamm I*, Trepel M*, Cardó-Vila M, Sun Y, Welsh K, Cabezas E, Swatterthwait A, Arap W, Reed JC, Pasqualini R: Peptides targeting caspase inhibitors. J. Biol. Chem. 278, 14401-14405, 2003.
- Engelhardt M, Jakob A, Rüter B, Trepel M, Hirsch F, Lübbert M: Severe cold hemagglutinin disease (CHD) successfully treated with rituximab. Blood 100, 1922-1923, 2002
- Arap W, Kolonin MG*, Trepel M*, Lahdenranta J, Cardo-Vila M, Giordano RJ, , Mintz PJ, Ardelt PU, Yao VJ, Vidal CI, Chen L, Flamm A, Valtanen H, Weavind LM, Hicks ME, Pollock RE, Botz GH, Bucana CD, Koivunen E, Cahill D, Troncoso P, Baggerly KA, Pentz RD, Do KA, Logothetis CJ, Pasqualini R: Steps towards mapping the human vasculature by phage display. Nature Medicine 8, 121-127, 2002
- Trepel M, Arap W, Pasqualini R: Modulation of humoral immune response by targeting antigens to lymph nodes. Cancer Research 61, 8110-8112, 2001
- Grifman M, Trepel M, Speece P, Gilbert LB, Arap W, Pasqualini R, Weitzman MD: Incorporation of tumor-targeting peptides into recombinant adeno-associated virus (rAAV) capsids. Molecular Therapy 3, 964-975, 2001
- Trepel M, Grifman M, Weitzman MD, Pasqualini R: Molecular adaptors for vascular-targeted adenoviral gene delivery. Hum. Gene Therapy 11, 1971-1981, 2000
- Trepel M, Groscurth P, Malipiero U, Gulbins E, Dichgans J, Weller M: Chemosensitivity of malignant glioma: modulation by p53 gene transfer. J. Neuro-Oncol. 39, 19-32, 1998
- Reber U, Wüllner U, Trepel M, Baumgart J, Seyfried J, Klockgether T, Dichgans J, Weller M: Potentiation of Treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells - the role of bcl-2. Biochem. Pharmacol. 55, 349-359, 1998
- Trepel M, Scheding S, Groscurth P, Horny HP, Malipiero U, Brugger W, Dichgans J, Weller M: A new look at the role of p53 in leukemia cell sensitivity to chemotherapy. Leukemia 11, 1842-1849, 1997
- Weller M, Trepel M, Grimmel C, Schabet M, Bremen D, Krajewski S, Reed JC: Hypericin-induced apoptosis of human malignant glioma cells is light-dependent, independent of bcl-2 expression, and does not require wild-type p53. Neurol. Res. 19, 459-470, 1997
- Wagenknecht B, Trepel M, von Deimling A, Grimmel C, Rollbrocker B, Hayashi Y, Lang F, Dichgans J, Gulbins E, Weller M: p53 accumulation promotes dephosphorylation and proteolytic cleavage of retinoblastoma protein in human malignant glioma cells. Cell Physiol. Biochem. 7, 304-311, 1997
- Roth W, Fontana A, Trepel M, Reed JC, Dichgans J, Weller M: Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics. Cancer Immunol. Immunother. 44, 55-63, 1997
- Trepel M, Weller M, Dichgans J, Petersen D: Voluntary facial palsy with a pontine lesion. J. Neurol. Neurosurg. Psychiatr. 61, 531-533, 1996
- Kolbinger W., Trepel M, Beyer C, Pilgrim C, Reisert I: The influence of genetic sex on sexual differentiation of diencephalic dopaminergic neurons in vitro and in vivo. Brain Res. 554, 349-352, 1991
- Halms T, Strasser M, Hasan A, Rüther T, Trepel M, Raab S, Gertzen M.: Smoking and quality of life in lung cancer patients: systematic review. BMJ Support. Palliat. Care, in press
- Dintner S, Schmutz M, Sommer S, Langer A, Hirschbühl K, Claus R, Schmid C, Trepel M, Märkl B: [NGS-based molecular genetics of leukemia-a powerful and decentralized approach][German]. Pathologie 44 (Suppl 3), 155-159, 2023
- Trepel M, Gerl A, Rieger C: Die individualisierung Der CLL-Erstlinientherapie mit Ibrutinib. Lehre und Praxis, 2022
- Hennigs JK, Matuszcak C, Trepel M, Körbelin J: Vascular Endothelial Cells: Heterogeneity and Targeting Approaches. Cells 10, 2712, 2021
- Voigtländer M, Schneider-Merck T, Trepel M: Lapatinib. Recent Results Cancer Res. 211, 19-44, 2018
- Fichtner M, Dreyling M, Binder M, Trepel M: The Role of B-Cell Antigen Receptors in Mantle Cell Lymphoma. J. Hematol. Oncol. 10, 164 (12 pages), 2017
- Kubuschok B, Trepel M: Learning from the failures of drug discovery in B-cell non-Hodgkin lymphomas and perspectives for the future: chronic lymphocytic leukemia and diffuse large B-cell lymphoma as two ends of a spectrum in drug development. Expert Opin Drug Discov. 7, 733-745, 2017
- Coßmann J, Trepel M: Klassifikation und aktuelle Therapiestrategien bei Non-Hodgkin-Lymphomen, Onkologische Pharmazie 19, 4-9, 2017
- Körbelin J, Schwaninger M, Trepel M: Vascular-targeted recombinant adeno-associated viral vectors for the treatment of rare diseases. Rare Diseases 4, e1220470 (5 pages), 2016
- Nolting M, Schneider-Merck T, Trepel M: Lapatinib. Recent Results Cancer Res. 201, 125-143, 2014
- Schneider-Merck T, Trepel M: Lapatinib. Recent Results Cancer Res. 184, 45-59, 2010
- Michelfelder S, Trepel M: Adeno-associated viral vectors and their redirection to cell-type specific receptors. Adv. Genet. 67, 29-60, 2009
- Binder M, Trepel M: Drugs targeting integrins for cancer therapy. Exp. Opin. Drug Discovery 4, 229-241, 2009
- Trepel M, Pasqualini R, Arap W: Screening phage-display peptide libraries for vascular targeted peptides, Meth. Enzymol. 445, 83-106, 2008
- Kohlschütter J, Michelfelder S, Trepel M: Drug delivery in acute myeloid leukemia. Expert Opin. Drug Deliv. 5, 653-663, 2008
- Arap W, Trepel M, Zetter BR, Pasqualini R: Innovations in prostate cancer research. Cancer Res. 68, 635-638, 2008
- Trepel M, Arap W, Pasqualini R: In vivo phage display and vascular heterogeneity: implications for targeted medicine. Current Opinion in Chemical Biology 6, 399-404, 2002
- Trepel M, Arap W, Pasqualini R: Exploring vascular heterogeneity for gene therapy targeting. Gene Therapy 7, 2059-2060, 2000
- Waidhauser J, Trepel M: Blutbildveränderungen und hämatologische Onkologie. In: Hasan A (Hrsg.): Praxishandbuch Somatik und Psyche. Elsevier, pp 197-208, 2024
- Seidel C, Nicolay NH, Trepel M, Jordan F, Barrantes-Freer A, Güresir E: ZNS-Tumoren. In: Honecker F, Claßen J, Preiß J, Dornoff W (Hrsg.): Taschenbuch Hämatologie und Onkologie. Zuckwerdt, pp 262-268, 2024
- Seidel C, Kortmann RD, Trepel M, Jordan F, Meixensberger J: ZNS-Tumoren. In: Honecker F, Claßen J, Preiß J, Dornoff W (Hrsg.): Taschenbuch Hämatologie und Onkologie. Zuckwerdt, pp 252-258, 2022
- Trepel M: Milztumoren. In: Dt. Krebsgesellschaft (Hrsg.): Gastrointestinale Tumoren. Elsevier, pp 443-447, 2018
- Brandt A, Trepel M: Ätiologische und pathogenetische Grundlagen der Krebsentstehung. In: Koch U, Mehnert A (Hrsg.): Handbuch der Psychoonkologie , Hogrefe, pp 31-41, 2016
- Müller F, Trepel M: Meningeosis neoplastica. In: Berger DP, Duyster J, Engelhardt M, Engelhardt R, Henß H, Mertelsmann R (Hrsg.): Das Rote Buch: Hämatologie und Internistische Onkologie, Ecomed, pp 1067-1071, 2013
- Trepel M: Meningeosis neoplastica. In: Berger DP, Engelhardt M, Engelhardt R, Henß H, Mertelsmann R (Hrsg.): Das Rote Buch: Hämatologie und Internistische Onkologie, Ecomed, pp 1007-1011, 2010
- Trepel M: Carcinomatous meningitis (leptomeningeal metastases). In: Berger DP, Engelhardt M, Henss H, Mertelsmann R (Eds.): Concise Manual of Hematology and Oncology, Springer, pp 764-767, 2008
- Behringer D, Waller CF, Trepel M: Breast cancer. In: Berger DP, Engelhardt M, Henss H, Mertelsmann R (Eds.): Concise Manual of Hematology and Oncology, Springer, pp 597-610, 2008
- Trepel M, Arap W, Pasqualini R: Selection, isolation, and identification of targeting peptides for ligand-directed gene delivery. In: Friedmann T, Rossi JJ (Eds.): DNA Delivery and Gene Transfer Vector Laboratory Manual, Cold Spring Harbor Press, pp 360-369, 2006
- Trepel M: Neuroanatomie (Lehrbuch), 8., vollst. überarbeitete Auflage. Elsevier, München (456 Seiten, 353 Abbildungen, 30 Tabellen), 2021
- Trepel M: Neuroanatomie (Lehrbuch), 7., vollst. überarbeitete Auflage. Urban & Fischer / Elsevier, München (436 Seiten, 347 Abbildungen, 30 Tabellen), 2017
- Trepel M: Neuroanatomie (Lehrbuch), 6., vollst. überarbeitete Auflage. Urban & Fischer / Elsevier, München (432 Seiten, 435 Abbildungen, 28 Tabellen), 2015
- Trepel M: Neuroanatomie (Lehrbuch), 5., vollst. überarbeitete Auflage. Urban & Fischer / Elsevier, München (420 Seiten, 435 Abbildungen, 28 Tabellen), 2011
- Trepel M: Neuroanatomie (Lehrbuch), 4., vollst. überarbeitete Auflage. Urban & Fischer / Elsevier, München, Jena (396 Seiten, 336 Abbildungen, 28 Tabellen), 2008
- Trepel M: Neuroanatomie (Lehrbuch), 3., vollst. überarbeitete Auflage. Urban & Fischer / Elsevier, München (450 Seiten, 285 Abbildungen, 27 Tabellen), 2003
- Trepel M: Neuroanatomie (Lehrbuch), 2. , vollst. überarbeitete Auflage. Urban & Fischer, München, Stuttgart, Jena (373 Seiten, 284 Abbildungen, 23 Tabellen), 1999
- Tepel M: Neuroanatomie (Lehrbuch). 1. Auflage Urban & Schwarzenberg, München, Wien, Baltimore (350 Seiten, 272 Abbildungen, 17 Tabellen), 1995