The focus of our research group is the precise characterization of the cellular immune status of patients with leukaemias and solid tumours. Depending on the clinical question, we quantitatively and functionally analyse a wide range of lymphocyte subpopulations from the B, T, and NK cell lineages. To achieve this, we employ immunophenotyping using flow cytometry. The material analysed typically comes from peripheral blood or bone marrow, but isolated cells from cell cultures or human fresh tissue can also be studied. Additionally, there is the possibility to analyse circulating tumour cells in the blood. In this context, the detection of surface proteins, which interact with immune cells, is of particular interest. To process the large volumes of data generated, we are increasingly using machine learning algorithms for data analysis.
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