Disposition for tumours in children and adolescents – Care4TuDos
Children, adolescents and adults with tumour predisposition syndromes
For a long time, it was assumed that cancer in children was the result of unfortunate circumstances. Today, however, we know that approximately 10% of affected children and adolescents have a condition known as tumour predisposition syndrome (TDS). TDS also plays an important role in adults with cancer. According to the latest research, it can be assumed that up to 25% of all patients with a tumour disease have TDS.
What is TDS?
TDS are genetic disorders associated with an increased risk of various benign and, above all, malignant tumours.
TDS can be inherited or newly developed in affected patients.
The possibilities for testing affected children, adolescents and adults for such a genetic predisposition are constantly increasing.
According to the recommendations of the German Paediatric Oncology and Haematology Society (GPOH) and the German Cancer Society (DKG), all children and adolescents with a newly diagnosed cancer should be screened for signs of TDS using a questionnaire.
If abnormalities are found, genetic counselling and, if necessary, testing are recommended.
TDS Competence Centre
Affiliated with the Swabian Paediatric Cancer Centre (Augsburg University Hospital) and the Augsburg Centre for Rare Diseases, we have established a centre of excellence in Bavaria (ZeKiTDS) for children, adolescents and adults with tumour predisposition syndromes, where, patients with tumour diseases can be diagnosed and treated with regard to TDS.
With a team of doctors, psychologists and scientists, we aim to develop new diagnostic and preventive options as well as comprehensive care structures for affected individuals and their families. This is complemented by extensive research activities (the Care4TuDoS study), which aim to contribute to a better understanding of cancer development and early detection, as well as better care for those affected according to their individual needs.
How to contact us!
The long-term goal is to improve the living conditions of children, adolescents and adults with TDS in the long term through a combination of research, therapy and care.
Team
Prof. Dr. Michaela Kuhlen
Dr. Daniela Angelova-Toshkina, MD
Daniela Pfeiffer, M.Sc.
Funding
German Research Foundation. Intramural research funding from the Medical Faculty of the University of Augsburg. PLGA Foundation.